Table 1.
Correlation between LRH1 protein expression level and clinicopathological variables in 133 patients with OC.
| Variables | All patientsn = 133 | LRH1 expression level | P | |
|---|---|---|---|---|
| Low (%) (n = 59) | High (%) (n = 74) | |||
| Age (years) | 0.252 | |||
| ≤52 | 67 | 33 (49.3) | 34 (50.7) | |
| >52 | 66 | 26 (39.4) | 40 (60.6) | |
| Histological type Serous |
92 | 42 (45.7) | 50 (54.3) | 0.653 |
| Others | 41 | 17 (41.5) | 24 (58.5) | |
| FIGO stage | 0.001 | |||
| I/II | 28 | 20 (71.4) | 8 (28.6) | |
| III/IV | 105 | 39 (37.1) | 66 (62.9) | |
| Histologic grade | 0.310 | |||
| G1/G2 | 50 | 25 (50.0) | 25 (50.0) | |
| G3 | 83 | 34 (41.0) | 49 (59.0) | |
| Residual disease (cm) | 0.851 | |||
| <1 | 98 | 43 (43.9) | 55 (56.1) | |
| ≥1 | 35 | 16 (45.7) | 19 (54.3) | |
| Ascites (ml) | 0.473 | |||
| <100 | 38 | 15 (39.5) | 23 (60.5) | |
| ≥100 | 95 | 44 (46.3) | 51 (53.7) | |
| Serum CA-125 level (U/ml) | 0.653 | |||
| ≤35 | 41 | 17 (41.5) | 24 (58.5) | |
| >35 | 92 | 42 (45.7) | 50 (54.3) | |
| Lymph node metastasis | 0.011 | |||
| No | 81 | 43 (53.1) | 38 (46.9) | |
| Yes | 52 | 16 (30.8) | 36 (69.2) | |
| Peritoneum metastasis | 0.001 | |||
| No | 43 | 28 (65.1) | 15 (34.9) | |
| Yes | 90 | 31 (34.4) | 59 (65.6) | |
| Platinum resistance | 0.037 | |||
| No | 67 | 33 (49.3) | 30 (50.7) | |
| Yes | 66 | 26 (39.4) | 44 (60.6) | |
FIGO, the Federation of Gynaecology and Obstetrics; G1, Well differentiated; G2, moderately differentiated; G3, poorly differentiated; OC, ovarian cancer.