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. 2020 Oct 20;11:586806. doi: 10.3389/fphar.2020.586806

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Copyright © 2020 Wei, Ma, Niu, Wang, Yang, Wang, Wen, Li and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PCA score plot of the normal, BDL, and PF (200 mg/kg) groups in the ESI+ mode (A) and ESI− mode (B). (C) Pairwise comparisons between the normal and BDL groups. (D) S-plots of the OPLS-DA model for the normal group and BDL group. (E) The 100-permutation test for the normal and BDL groups. (F) Pairwise comparisons between the BDL and PF groups. (G) S-plots of the OPLS-DA model for the BDL and PF groups. (H) The 100-permutation test for the BDL and PF groups. K, normal; M, model; PF, PFH.