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XGVHD after preemptive treatment with WT and ERBB2-CAR CIK cells.
| WT CIK (n = 6) | ErbB2-CAR CIK (n = 8) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liver | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Lung | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Spleen | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Gut | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Signs of tissue damage, necrosis or fibrosis assessed by HE staining: –, no signs; +, low signs; ++, medium signs of xGVHD.
