Table 1.
Demographic and clinical characteristics of elderly cystectomy patients.
| Variables | All patients (n = 342) | Non-AKI group (n = 232) | AKI group (n = 110) | P value∗ |
|---|---|---|---|---|
| Sex (male) | 280 (81.9) | 184 (79.3) | 96 (87.3) | 0.098 |
| Age (years) | 72.1 ± 4.9 | 71.9 ± 4.9 | 72.6 ± 4.7 | 0.221 |
| Body mass index (kg/m2) | 23.9 ± 3.1 | 23.9 ± 3.0 | 23.9 ± 3.3 | 0.975 |
| ASA physical status | 0.868 | |||
| ≤2 | 294 (86.0) | 200 (86.2) | 94 (85.5) | |
| 3 | 48 (14.0) | 32 (13.8) | 16 (14.5) | |
| Diabetes mellitus | 79 (23.1) | 56 (24.1) | 23 (20.9) | 0.583 |
| Hypertension | 175 (51.2) | 125 (53.9) | 50 (45.5) | 0.165 |
| Coronary artery disease | 27 (7.9) | 15 (6.5) | 12 (10.9) | 0.197 |
| Cerebrovascular disease | 16 (4.7) | 13 (5.6) | 3 (2.7) | 0.286 |
| COPD | 17 (5.0) | 10 (4.3) | 7 (6.4) | 0.431 |
| Smoking history | 0.876 | |||
| Nonsmoker | 169 (49.4) | 117 (50.4) | 52 (47.3) | |
| Current smoker | 26 (7.6) | 17 (7.3) | 9 (8.2) | |
| Ex-smoker | 147 (43.0) | 98 (42.2) | 49 (44.5) | |
| Tumor stage | 0.767 | |||
| 1 | 34 (9.9) | 22 (9.5) | 12 (10.9) | |
| 2 | 197 (57.6) | 138 (59.5) | 59 (53.6) | |
| 3 | 69 (20.2) | 44 (19.0) | 25 (22.7) | |
| 4 | 42 (12.3) | 28 (12.1) | 14 (12.7) | |
| Tumor grade | >0.999 | |||
| 2 | 9 (2.6) | 6 (2.6) | 3 (2.7) | |
| 3 | 333 (97.4) | 226 (97.4) | 107 (97.3) | |
| Neoadjuvant chemotherapy | 78 (22.8) | 59 (25.4) | 19 (17.3) | 0.100 |
| Preoperative laboratory tests | ||||
| White blood cells (103/μL) | 6.8 ± 2.7 | 6.6 ± 2.2 | 7.2 ± 3.4 | 0.037 |
| Hemoglobin (g/dL) | 11.9 ± 1.9 | 12.2 ± 1.9 | 11.4 ± 1.9 | <0.001 |
| Platelets (103/μL) | 241.9 ± 84.2 | 245.8 ± 81.4 | 235.6 ± 89.8 | 0.209 |
| Albumin (g/dL) | 3.6 ± 0.5 | 3.7 ± 0.4 | 3.4 ± 5.5 | 0.001 |
| Creatinine (mg/dL) | 1.0 ± 0.4 | 1.0 ± 0.3 | 1.1 ± 0.4 | 0.032 |
| eGFR (mL/min/1.73m2) | 72.7 ± 15.6 | 73.6 ± 15.9 | 70.9 ± 15.0 | 0.134 |
| Sodium (mmol/L) | 139.4 ± 3.1 | 139.6 ± 2.7 | 139.0 ± 3.8 | 0.099 |
| Potassium (mmol/L) | 4.4 ± 0.4 | 4.4 ± 0.4 | 4.4 ± 0.4 | 0.346 |
| Chloride (mmol/L) | 104.4 ± 3.5 | 104.4 ± 3.1 | 104.4 ± 4.2 | 0.959 |
| Uric acid (mg/dL) | 5.1 ± 1.5 | 5.1 ± 1.5 | 5.2 ± 1.6 | 0.838 |
| CRP (mg/dL) | 1.0 ± 2.2 | 0.4 ± 0.4 | 2.2 ± 3.4 | <0.001 |
| CRP/albumin ratio | 0.33 ± 0.86 | 0.10 ± 0.13 | 0.79 ± 1.40 | <0.001 |
Continuous variables are presented as the mean ± standard deviation and categorical variables as number (%). ∗For comparisons between the AKI and non-AKI groups. AKI: acute kidney injury; ASA: American Society of Anesthesiologists; COPD: chronic obstructive pulmonary disease; eGFR: estimated glomerular filtration rate; CRP: C-reactive protein.