Table 3.
Univariate and multivariate logistic regression analyses of risk factors for acute kidney injury after radical cystectomy among elderly patients.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Sex (female) | 0.559 (0.293–1.065) | 0.077 | ||
| Age | 1.029 (0.983–1.078) | 0.221 | ||
| Body mass index | 1.001 (0.931–1.077) | 0.975 | ||
| ASA physical status | ||||
| ≤2 | 1.000 | |||
| 3 | 1.064 (0.556–2.034) | 0.852 | ||
| Diabetes mellitus | 0.831 (0.480–1.439) | 0.508 | ||
| Hypertension | 0.713 (0.452–1.125) | 0.146 | ||
| Coronary artery disease | 1.771 (0.799–3.925) | 0.159 | ||
| Cerebrovascular accident | 0.472 (0.132–1.693) | 0.249 | ||
| COPD | 1.509 (0.559–4.076) | 0.417 | ||
| Tumor stage | ||||
| 1 | 1.000 | |||
| 2 | 0.784 (0.364–1.687) | 0.533 | ||
| 3 | 1.042 (0.442–2.456) | 0.926 | ||
| 4 | 0.917 (0.354–2.375) | 0.858 | ||
| Tumor grade | ||||
| 2 | 1.000 | |||
| 3 | 0.947 (0.232–3.859) | 0.939 | ||
| Neoadjuvant chemotherapy | 0.612 (0.344–1.089) | 0.095 | ||
| White blood cells | 1.091 (1.003–1.186) | 0.042 | ||
| Hemoglobin | 0.804 (0.710–0.910) | 0.001 | ||
| eGFR | 0.989 (0.975–1.003) | 0.135 | ||
| Uric acid | 1.016 (0.874–1.181) | 0.837 | ||
| CRP/albumin ratio | 20.398 (6.379–65.227) | <0.001 | 21.747 (6.506–72.683) | <0.001 |
| Operation duration | 1.001 (0.999–1.003) | 0.313 | ||
| Crystalloid amount | 1.001 (0.991–1.011) | 0.826 | ||
| 6% hydroxyethyl starch amount | 1.054 (1.020–1.089) | 0.002 | 1.053 (1.014–1.093) | 0.007 |
| Red blood cell transfusion | 2.086 (1.292–3.370) | 0.003 | ||
| Estimated blood loss | 1.000 (1.000–1.001) | 0.475 | ||
| Intraoperative hypotension | 1.146 (0.596–2.205) | 0.683 | ||
| Urinary diversion type | ||||
| Ileal conduit | 1.000 | |||
| Ileal neobladder | 0.555 (0.349–0.882) | 0.013 | ||
| Postoperative urinary infection | 1.018 (0.592–1.751) | 0.948 | ||
| Postoperative urinary tract obstruction | 0.000 (0.000–0.000) | >0.999 | ||
| Postoperative NSAID use | 1.422 (0.902–2.241) | 0.130 | ||
OR: odds ratio; CI: confidence interval; ASA: American Society of Anesthesiologists; COPD: chronic obstructive pulmonary disease; eGFR: estimated glomerular filtration rate; CRP: C-reactive protein; NSAID: nonsteroidal anti-inflammatory drug. Multivariate logistic regression analysis included white blood cells, hemoglobin, CRP/albumin ratio, 6% hydroxyethyl starch amount, red blood cell transfusion, and urinary diversion type from the univariate logistic regression analysis.