Table 1.
Effects of coadministered isoorientin (ISO) and LiC1 in RAW264.7 cells (mean ± SEM, n = 3).
| Compounds (μM) | Inhibition (%) Ea or Eb ± SEM |
Compounds (μM) | Inhibition (%) Ea+b ± SEM |
Q values |
|---|---|---|---|---|
| ISO 6.25 | E a 16.6 ± 6.5a | ISO 6.25+LiC1 25 | 10.1 ± 3.3 | 0.31 |
| ISO 25 | E a 29.8 ± 3.6a | ISO 6.25+LiC1 100 | 27.6 ± 7.9 | 0.79 |
| LiC 25 | E b 18.8 ± 3.3a | ISO 25+LiC1 25 | 28.8 ± 9.9 | 0.67 |
| LiC1 100 | E b 21.7 ± 6.1a | ISO 25+LiC1 100 | 35.0 ± 9.3 | 0.78 |
RAW264.7 cells were treated with isoorientin (6.25 and 25 μM) without or with LiCl (0, 25, and 100 μM) for 30 min and then stimulated with LPS (50 ng/mL). After 8 h stimulation, cell supernatants were collected, and the levels of TNF-α were detected by ELISA. The data were expressed as mean ± SEM (n = 3, 3 replicates). aP < 0.05 in comparison with the LPS group.