Table 1.

Compounds used in this study

ASOs 1, 2, 3, 4 and 6 have been previously described (58,86). Color code for ASO chemical modifications: black = unmodified deoxyribose (2′H). orange = 2′ methoxyethyl (MOE). blue = 2′-4′ constrained ethyl (cET). Unmarked backbone linkages = phosphorothioate (PS); linkages marked with o = normal phosphodiester (PO). mC = 5-methylcytosine.