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. 2020 Oct 12;48(19):10726–10738. doi: 10.1093/nar/gkaa854

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — The kinetic FFS study of DNA 8-mer formation in different crowding conditions. (A–C) The illustrations show typical configuration at the three interfaces used to calculate transition rates for the hybridization process: (A) proximity between complementary bases, (B) the first base pair formed, (C) all 8 bp formed. The grey, isolated particles are crowders with the same radius, shown in perspective view. (D–F) The relative reaction flux/transition probabilities across the three interfaces, respectively. (G–H) The relative k_on and k_off for 8-mer duplex formation.