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. 2020 Oct 12;48(19):10726–10738. doi: 10.1093/nar/gkaa854

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — The kinetic study of hairpin closing with the crowder-oxDNA model. (A–C) A typical DNA hairpin formation process represented in three stages: (A) the stem bases getting close, (B) the formation of first base pair and (C) the full base pairing of the stem. (D–F) The relative reaction rate of the three stages, respectively. (G–H) the overall relative k_on and k_off.