Table 4.
Multiple logistic regression analysis for the association between ABO blood groups and HR after AMI
| β | OR (95% CI) | P value | |
|---|---|---|---|
| Model 1 | |||
| Blood group A | 1.023 | 2.781 (1.174–7.198) | 0.035 |
| Age, years | 1.68 | 4.397 (1.698–11.578) | 0.001 |
| Female | 0.13 | 1.139 (1.065–1.218) | < 0.001 |
| Heart rate at admission, bpm | 0.053 | 1.054 (1.023–1.086) | 0.001 |
| BMI, kg/m2 | − 0.127 | 0.881 (0.764–1.015) | 0.079 |
| SBP, mmHg | − 0.013 | 0.987 (0.969, 1.006) | 0.179 |
| Model 2 | |||
| Blood group A | 0.895 | 2.448 (1.121–5.869) | 0.045 |
| Age, years | 0.803 | 2.232 (0.913–5.445) | 0.78 |
| Female | 0.171 | 1.187 (1.102–1.278) | < 0.001 |
| ESR, mm/h | 0.051 | 1.053 (1.017–1.09) | 0.003 |
| BNP, pg/ml | 0.01 | 1.011 (0.997–1.019) | 0.853 |
| CTnI, ng/ml | 0.007 | 1.007 (0.999–1.015) | 0.088 |
| Model 3 | |||
| Blood group A | 0.697 | 2.107 (1.065–4.568) | 0.046 |
| Age, years | 1.324 | 3.757 (1.548–9.12) | 0.003 |
| Female | 0.129 | 1.138 (1.065–1.215) | 0.001 |
| LVEF, % | − 0.064 | 0.938 (0.902–0.977) | 0.002 |
| Model 4 | |||
| Blood group A | 0.73 | 2.075 (1.002–4.288) | 0.048 |
| Age, years | 0.863 | 2.371 (1.035–5.433) | 0.031 |
| Female | 0.132 | 1.141 (1.07–1.217) | 0.002 |
| No pPCI treatment | 1.072 | 2.928 (1.418–7.344) | 0.005 |
| Model 5 | |||
| Blood group A | 0.687 | 2.212 (1.064–5.168) | 0.039 |
| GRACE RS | 0.019 | 1.02 (1.01–1.029) | < 0.001 |
Italicized value indicates that blood group A was significantly associated with an elevated risk of HR after AMI in different models
HR, heart rupture; AMI, acute myocardial infarction; OR, odds ratio; CI, Confidence interval; BMI, body mass index; SBP, systolic blood pressure; ESR, erythrocyte sedimentation rate; BNP, brain natriuretic peptide; CTnI, cardiac troponin I; LVEF, left ventricular ejection fraction; pPCI, primary primary percutaneous coronary intervention; GRACE RS, Global Registry of Acute Coronary Events risk score
Variables included in model 1 are blood group A, age, female gender, heart rate at admission, BMI and SBP
Variables included in model 2 are blood group A, age, female gender, ESR, BNP and CTnI
Variables included in model 3 are blood group A, age, female gender and LVEF
Variables included in model 4 are blood group A, age, female gender and no pPCI treatment
Variables included in model 5 are blood group A and the GRACE RS