Table 2.

Coefficient and 95% confidence intervals for the effect of diabetes on the pulmonary function

	DM with Hba1c < 7				DM with Hba1c > = 7
	FEV1	PC	FVC	PC	FEV1	PC	FVC	PC
Model 1 adjusted for	− 6.54 [− 8.17, − 4.91]		− 7.21 [− 8.94, − 5.47]		− 6.68 [− 8.83, − 4.53]		− 9.17 [− 11.47, − 6.87]
Additionally adjusted for
HbA1c	− 4.17 [− 6.03, − 2.32]	36.3%	− 4.71 [− 6.66, − 2.77]	34.6%	− 4.88 [− 8.35, − 1.41]	31.1%	− 7.20 [− 10.73, − 3.67]	24.7%
FPG	− 4.62 [− 8.16, − 1.10]	32.5%	− 5.89 [− 9.22, − 2.56]	21.2%	− 4.83 [− 9.71, 0.06]	24.2%	− 7.22 [− 12.23, − 2.21]	17.1%
2 h-PG	− 3.19 [− 8.02, 1.65]	40.3%	− 3.55 [− 8.10, 1.01]	43.2%	IO	IO	IO	IO
log (HOMA-IR)	− 5.81 [− 8.77, − 2.85]	15.4%	− 5.33 [− 8.12, − 2.54]	26.9%	− 5.33 [− 8.06, − 2.59]	19.7%	− 6.83 [− 9.47, − 4.19]	23.5%
BMI	− 6.01 [− 7.91, − 4.30]	6.7%	− 6.39 [− 7.97, − 4.81]	11.5%	− 6.12[ − 8.18, − 4.07]	8.6%	− 8.24 [− 10.10, − 6.38]	10.4%
waist circumference	− 5.62 [− 7.41, − 3.83]	15.5%	− 6.06 [− 7.67, − 4.45]	17.6%	− 5.21 [− 7.25, − 3.17]	20.6%	− 7.55 [− 9.42, − 5.67]	17.6%
log (C-reactive protein)	− 4.89 [− 6.70, − 3.08]	12.7%	− 5.97 [− 7.75, − 4.18]	12.0%	− 4.92 [− 7.69, − 2.15]	24.8%	− 8.46 [− 10.85, − 6.06]	11.3%

PC Percentage mediation, IO insufficient observation, FPG fasting plasma glucose, 2 h-PG plasma glucose 2 h after OGTT, HOMA-IR homeostasis model of assessment for insulin resistance index

Model 1 adjusted age, race, sex, education, and METs