Table 1.
Baseline participant characteristics.
ESM-trial (n = 19) | RCT Stop (n = 24) | RCT Go (n = 20) | Cohort (n = 94) | |
---|---|---|---|---|
Mean age in years (SD) | 32.3 (4.8) | 31.6 (5.3) | 31.4 (4.3) | 31.3 (4.3) |
Nulliparous (%) | 2 (15) | 3 (20) | 1 (8) | 7 (16) |
Born in the Netherlands (%)a | 18 (100) | 22 (100) | 14 (87) | 89 (99) |
Marital status | ||||
Single (%) | 1 (5.3) | 1 (4) | 1 (5) | 3 (3) |
Partner, living apart (%) | 1 (5.3) | 1 (4) | 1 (5) | 5 (5) |
Married or cohabiting(%) | 17 (89) | 22 (92) | 17 (89) | 86 (91) |
Smoking (%) | 2 (10) | 3 (12) | 1 (5) | 5 (5) |
Education | ||||
Primary school or Secondary education (%) | 0 (0) | 1 (4) | 1 (5) | 4 (4) |
Vocational or Pre-university education (%) | 8 (44) | 11 (46) | 8 (40) | 27 (30) |
Higher education (%) | 10 (56) | 12 (50) | 11 (55) | 58 (65) |
Duration ADM usage, in months (SD) | 72.9 (59.0) | 56.0 (50.0) | 50.6 (38.0) | 72.3 (65.0) |
Number of previous MDD episodes (SD) | 1.9 (1.0) | 2.2 (1.2) | 1.9 (1.5) | 1.9 (1.5) |
Comorbid DSM-IV Axis-I disorders, yes (%) | 7 (37) | 9 (37) | 7 (35) | 28 (29) |
Mean EPDS score (SD) | 5.5 (3.3) | 6.3 (3.6) | 4.5 (3.1) | 6.5 (4.4) |
Mean STAI score | ||||
STAI—state (SD) | 33.3 (9.1) | 34.0 (8.2) | 32.6 (7.6) | 35.2 (9.5) |
STAI—trait (SD) | 39.5 (7.8) | 39.3 (7.1) | 35.4 (6.5) | 40.4 (9.6) |
Mean PANAS score | ||||
Positive affect (SD) | 2.1 (0.6) | 2.0 (0.6) | 2.2 (0.7) | 2.0 (0.7) |
Negative affect (SD) | 0.7 (0.7) | 0.8 (0.7) | 0.5 (0.5) | 0.9 (0.7) |
Not all information is available for each participant, resulting in small variations of percentages. Numbers are rounded. RCT, Randomized controlled trial; RCT Stop, RCT group receiving preventive cognitive therapy while tapering ADM; RCT Go, RCT group continuing ADM; ADM, antidepressant medication; ESM, experience sampling methodology; HRSD-17, Hamilton Rating Scale for Depression−17 items; MDD, major depressive disorder; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders fourth edition; EPDS, Edinburgh post-natal depression scale, STAI, state-trait anxiety inventory; PANAS, positive and negative affect scale.
Chi-square indicates significant differences between RCT Stop, RCT Go, and Cohort group (p = 0.02).