Supplement Table 1.
Proportion of the population and subgroups at various Lp(a) thresholds (≥30, ≥50, ≥70, and ≥90 mg/dL)
| ≥ 30 mg/dL | ≥ 50 mg/dL | ≥ 70 mg/dL | ≥ 90 mg/dL | |||||
|---|---|---|---|---|---|---|---|---|
| Percentage (95% CI) | P-value | Percentage (95% CI) | P-value | Percentage (95% CI) | P-value | Percentage (95% CI) | P-value | |
| Entire population (n = 8722) | 27.8% (26.3%, 29.3%) | - | 14.7% (13.6%, 15.9%) | - | 5.6% (5.0%, 6.3%) | - | 2.6% (2.2%, 3.1%) | - |
| Age | - | .29 | - | .02 | - | .049 | - | .08 |
| <35 (n = 3091) | 27.1% (24.6%,29.7%) | - | 13.2% (11.4%, 15.1%) | - | 4.7% (3.7%, 5.9%) | - | 2.2% (1.6%, 3.2%) | - |
| 35–54 (n = 2548) | 27.5% (25.0%, 30.3%) | - | 14.5% (12.6%, 16.5%) | - | 5.6% (4.6%, 6.9%) | - | 2.4% (1.8%, 3.3%) | - |
| 55–74 (n = 2092) | 27.9% (25.3%, 30.8%) | - | 17.1% (15.0%, 19.4% | - | 7.0% (5.8%, 8.5%) | - | 3.7% (2.8%, 4.9%) | - |
| 75+ (n = 991) | 32.7% (29.0%, 36.7%) | - | 18.0% (15.1%, 21.3%) | - | 6.1% (5.0%, 6.3%) | - | 2.9% (1.9%, 4.3%) | - |
| Sex | - | .003 | - | .002 | - | .02 | - | .07 |
| Male (n = 3811) | 25.4% (23.2%, 27.7%) | - | 12.9% (11.3%, 14.6%) | - | 4.8% (3.9%, 5.8%) | - | 2.2% (1.6%, 2.9%) | - |
| Female (n = 4911) | 30.0% (28.0%, 32.0%) | - | 16.4% (15.0%, 17.9%) | - | 6.3% (5.5%, 7.3%) | - | 3.1% (2.5%, 3.8%) | - |
| Race/ethnicity | - | <.001 | - | <.001 | - | <.001 | - | <.001 |
| Non-Hispanic white(n = 3356) | 24.3% (22.5%, 26.2%) | - | 11.9% (10.6%, 13.3%) | - | 3.9% (3.2%, 4.8%) | - | 1.7% (1.3%, 2.4%) | - |
| Non-Hispanic black (n = 2585) | 60.0% (57.9%, 62.1%) | - | 39.0% (36.9%, 41.1%) | - | 19.7% (18.0%, 21.4%) | - | 9.9% (8.7%, 11.2%) | - |
| Mexican American (n = 2364) | 16.0% (14.4%, 17.8%) | - | 7.3% (6.2%, 8.6%) | - | 2.2% (1.6%, 2.9%) | - | 0.7% (0.4%, 1.1%) | - |
| Other (n = 417) | 23.7% (18.6%, 29.8%) | - | 12.6% (8.9%, 17.7%) | - | 4.0% (2.2%, 7.0%) | - | 2.2% (0.9%, 5.2%) | - |
| MI | - | .04 | - | <.001 | - | <.001 | - | <.001 |
| No (n = 8359) | 27.5% (26.0%, 29.1%) | - | 14.4% (13.3%, 15.5%) | - | 5.3% (4.7%, 6.0%) | - | 2.5% (2.1%, 2.9%) | - |
| Yes (n = 358) | 34.9% (27.9%, 42.7%) | - | 25.4% (189%, 33.1%) | - | 13.1% (8.2%, 20.3%) | - | 7.8% (4.0%, 14.7%) | - |
| Stroke | - | .95 | - | .09 | - | .02 | - | .02 |
| No (n = 8441) | 27.8% (26.3%, 29.3%) | - | 14.6% (13.5%, 15.8%) | - | 5.5% (4.9%, 6.2%) | - | 2.6% (2.1%, 3.1%) | - |
| Yes (n = 276) | 27.5% (20.8%,35.5%) | - | 19.7% (14.0%, 27.1%) | - | 10.5% (6.2%, 17.1%) | - | 6.2% (3.0%, 12.5%) | - |
CI, confidence interval; Lp(a), lipoprotein (a); MI, myocardial infarction.