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Genomic context of SMARCA4 alterations. (A) Most frequent co-occurring alterations by SMARCA4 alteration. (B) Distribution of SMARCA4 alteration by commonly altered gene subgroups in NSCLC. (C) Frequency of altered individual genes within SMARCA4 mutant vs SMARCA4 wildtype subgroups. Genes labeled red were associated with significantly differential PD-L1 expression (q value <0.10). (D) Distribution of SMARCA4, STK11, KRAS, and KEAP1 alterations within NSCLC cohort.
