Table 1:

Summary of key articles using patient-reported outcome (PRO) measures in CLE patients

References	Main Objective	Country	Sample size	Type of PROs used	Key findings
Vasquez et al.1	To compare quality of life (QoL) indicators between patients with CLE at the University of Texas Southwestern (UTSW) Medical Center at Dallas and those at the University of Pennsylvania (UPenn)	USA	248	Modified Skindex-29+3, SF-36	Female gender, low annual income levels (<$10,000), low levels of education (high school education), presence of SLE, and increased disease activity were all associated with poor QoL.
Ishiguro et al.2	To assess whether the skin symptoms in CLE are associated with the QoL using the Japanese version of the Skindex-29.	Japan	54	Skindex	Female gender, older age, and longer duration of systemic lupus erythematosus (SLE) were correlated with poor QoL.
Klein et al.3	To determine how CLE affects QoL and which independent variables are associated with poor QoL.	USA	157	Skindex-29, SF-36	Female gender, generalized disease, severe disease, distribution of lesions, and younger age were factors realted to poor QoL.
Teske et al.4	To identify demographic and clinical variables associated with decreased QoL in patients with discoid lupus erythematosus (DLE).	USA	117	Modified Skindex-29+3	Female gender and smoking were correlated with impairment of multiple domains of quality of life in DLE.
Mendez-Flores5	To evaluate the association of pain and pruritus with dermatologic QoL and cutaneous disease activity in patients with 1) specific cutaneous lupus erythematosus (CLE) lesions, 2) nonspecific CLE lesions and 3) both types of CLE lesions.	Mexico	42	Dermatology Life Quality Index (DLQI), pain and pruritus, visual analog scales (VAS)	Pain, not pruritus, correlated with dermatologic QoL and cutaneous activity.