Table 5.
Cumulative percentage in patients in the BPaMZ group with rifampicin-resistant tuberculosis and culture negative overnight sputum samples, and the median time to sputum culture conversion
Pyrazinamide-susceptible rifampicin-resistant tuberculosis (n=38) | Pyrazinamide-resistant | rifampicin-resistant tuberculosis (n=22) | |
---|---|---|---|
Percentage culture negative at day 56 of treatment (95% CI) | |||
Liquid culture | 96·0% (88·5–100·0) | 79·8% (62·4–97·2) | |
Solid culture | 100·0% (100·0–100·0) | 95·0% (85·3–100·0) | |
Liquid culture median (IQR) time to culture negative, days | 41 (35–56) | 49 (34–56) |
BPaMZ=bedaquiline (daily dose), pretomanid, and pyrazinamide plus moxifloxacin.