Table 1.
Baseline characteristics among colorectal cancer patients by quartile of plasma vitamin D binding protein
|
Characteristic |
Vitamin D binding protein | |||
|---|---|---|---|---|
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |
| No. of patients | 149 | 151 | 152 | 151 |
| Age at blood collection, mean (SD), years | 61.2 (7.8) | 62.3 (8.1) | 60.9 (8.3) | 60.9 (8.5) |
| Age at diagnosis, mean (SD), years | 71.3 (7.6) | 71.9 (8.5) | 71.0 (8.4) | 70.9 (8.8) |
| Time from blood collection to diagnosis, mean (SD), years | 10.1 (4.9) | 9.7 (4.6) | 10.1 (4.7) | 9.9 (5.1) |
| Sex, No. (%) | ||||
| Female | 89 (59.7) | 89 (58.9) | 90 (59.2) | 89 (58.9) |
| Male | 60 (40.3) | 62 (41.1) | 62 (40.8) | 62 (41.1) |
| Body mass index, mean (SD), kg/m2 | 26.9 (5.1) | 25.8 (3.7) | 25.6 (4.3) | 25.2 (3.6) |
| Physical activity, mean (SD), MET-h/wk | 22.1 (21.0) | 26.4 (36.8) | 24.5 (33.2) | 25.7 (29.8) |
| Cancer stage, No. (%) | ||||
| I | 39 (26.2) | 40 (26.5) | 39 (25.7) | 41 (27.2) |
| II | 39 (26.2) | 37 (24.5) | 34 (22.4) | 38 (25.2) |
| III | 33 (22.1) | 30 (19.9) | 30 (19.7) | 31 (20.5) |
| IV | 16 (10.7) | 21 (13.9) | 30 (19.7) | 21 (13.9) |
| Unknown | 22 (14.8) | 23 (15.2) | 19 (12.5) | 20 (13.2) |
| Grade of tumor differentiation, No. (%) | ||||
| Well differentiated | 16 (10.7) | 14 (9.3) | 17 (11.2) | 17 (11.3) |
| Moderately differentiated | 86 (57.7) | 90 (59.6) | 89 (58.6) | 84 (55.6) |
| Poorly differentiated | 24 (16.1) | 19 (12.6) | 18 (11.8) | 25 (16.6) |
| Unknown | 23 (15.4) | 28 (18.5) | 28 (18.4) | 25 (16.6) |
| Location of primary tumor, No. (%) | ||||
| Proximal colon | 66 (44.3) | 57 (37.7) | 75 (49.3) | 72 (47.7) |
| Distal colon | 42 (28.2) | 43 (28.5) | 36 (23.7) | 42 (27.8) |
| Rectum | 32 (21.5) | 38 (25.2) | 33 (21.7) | 27 (17.9) |
| Unknown | 9 (6.0) | 13 (8.6) | 8 (5.3) | 10 (6.6) |
| Year of diagnosis, No. (%) | ||||
| 1991–2000 | 68 (45.6) | 78 (51.7) | 66 (43.4) | 67 (44.4) |
| 2001–2011 | 81 (54.4) | 73 (48.3) | 86 (56.6) | 84 (55.6) |
| Season of blood collection, No. (%) | ||||
| Summer (June, July, August) | 45 (30.2) | 46 (30.5) | 48 (31.6) | 53 (35.1) |
| Fall (September, October, November) | 41 (27.5) | 47 (31.1) | 43 (28.3) | 41 (27.2) |
| Winter (December, January, February) | 33 (22.1) | 26 (17.2) | 28 (18.4) | 26 (17.2) |
| Spring (March, April, May) | 30 (20.1) | 32 (21.2) | 33 (21.7) | 31 (20.5) |
Abbreviations: MET, metabolic equivalent; SD, standard deviation.