Table 4.

The association between manual qualitative terminal duct lobular unit (TDLU) categories and breast cancer risk was evaluated using unconditional logistic regression models to estimate odd ratios (ORs) and 95% confidence intervals (CI). Model 1 adjusted for matching factors. Model 2 adjusted for matching factors and benign breast disease (BBD) histological subtypes.

	Cases/Controls n	Model 1	Model 2
Among women with both quantitative and qualitative data
No type 1 lobules	23/114	Ref	Ref
Mixed lobule types	93/409	1.25 (0.76,2.14)	1.15 (0.69,1.98)
Predominant type 1 and no type 3 lobules	61/334	0.95 (0.54,1.70)	0.95 (0.54,1.71)
No type 1 lobules or mixed lobule types	116/523	Ref	Ref
Predominant type 1 and no type 3 lobules	61/334	0.79 (0.54,1.13)	0.84 (0.58,1.22)
Women in full BBD nested case-control study with qualitative data
No type 1 lobules	41/192	Ref	Ref
Mixed lobule types	151/640	1.17 (0.79,1.74)	1.09 (0.74,1.65)
Predominant type 1 and no type 3 lobules	96/542	0.82 (0.53,1.28)	0.86 (0.56,1.35)
No type 1 lobules or mixed lobule types	192/832	Ref	Ref
Predominant type 1 and no type 3 lobules	96/542	0.72 (0.54,0.96)	0.80 (0.59,1.07)