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. 2020 Oct 28;86(22):e01446-20. doi: 10.1128/AEM.01446-20

TABLE 5.

KEGG enrichment analyses

KEGG no. Description Transcriptomics
Proteomics
t3
t4
t5
t3
t4
t5
P value (adjusted) Gene count P value (adjusted) Gene count P value (adjusted) Gene count P value (adjusted) Protein count P value (adjusted) Protein count P value (adjusted) Protein count
ko01230 Biosynthesis of amino acids 3.31E−34 48 2.73E−31 33 8.13E−23 31 3.74E−05 7 5.80E−03 5 5.69E−06 10
ko03010 Ribosome 2.11E−13 23 2.54E−05 9 8.77E−03 7 4.91E−06 7 4.42E−16 16
ko00230 Purine metabolism 4.74E−10 23 2.66E−02 6 5.00E−05 12 1.45E−07 9 4.49E−04 6
ko00220 Arginine biosynthesis 4.06E−07 11 3.13E−07 8 5.51E−06 8
ko00250 Alanine, aspartate, and glutamate metabolism 2.08E−06 11 8.77E−03 5 4.83E−02 2
ko00270 Cysteine and methionine metabolism 5.12E−06 13 1.00E−02 5 4.34E−02 5 2.39E−02 4
ko01210 2-Oxocarboxylic acid metabolism 7.86E−06 11 1.27E−09 11 5.51E−06 9 3.74E−05 5 1.20E−02 3 8.75E−03 4
ko00240 Pyrimidine metabolism 4.65E−05 11 2.37E−05 9
ko01200 Carbon metabolism 6.22E−05 21 2.92E−03 10 1.24E−02 5
ko03440 Homologous recombination 1.14E−04 9 2.92E−04 4 4.10E−02 3
ko03430 Mismatch repair 2.10E−04 7 6.10E−05 4 1.30E−03 4
ko00521 Streptomycin biosynthesis 2.40E−04 5
ko00340 Histidine metabolism 2.40E−04 7 1.64E−09 9 8.79E−08 9
ko02024 Quorum sensing 2.82E−04 17 9.30E−03 8
ko00061 Fatty acid biosynthesis 7.07E−04 6 4.34E−02 3
ko03060 Protein export 7.07E−04 6 1.68E−02 3
ko00260 Glycine, serine, and threonine metabolism 8.68E−04 9
ko00300 Lysine biosynthesis 1.43E−03 6 1.14E−04 6
ko03420 Nucleotide excision repair 1.72E−03 6
ko00550 Peptidoglycan biosynthesis 2.07E−03 6 1.62E−06 8
ko00290 Valine, leucine, and isoleucine biosynthesis 2.44E−03 4 1.31E−04 4 5.08E−04 4 1.44E−04 3 1.20E−02 2
ko00670 One-carbon pool by folate 3.16E−03 5 4.06E−02 3 1.74E−02 2
ko00710 Carbon fixation in photosynthetic organisms 3.16E−03 5
ko03030 DNA replication 5.17E−03 6 3.36E−03 3 2.81E−02 3
ko03070 Bacterial secretion system 1.47E−02 6
ko00620 Pyruvate metabolism 1.76E−02 7 3.49E−02 5
ko00900 Terpenoid backbone biosynthesis 2.32E−02 5 2.63E−02 4
ko01212 Fatty acid metabolism 2.46E−02 6
ko00770 Pantothenate and CoA biosynthesis 2.53E−02 4 1.72E−03 4 7.44E−03 4 1.76E−02 2 3.23E−02 2
ko01502 Vancomycin resistance 3.00E−02 3
ko00970 Aminoacyl-tRNA biosynthesis 3.28E−02 5 1.42E−06 9
ko00020 Citrate cycle (TCA cycle) 7.05E−05 6 3.65E−02 2 2.90E−03 4
ko00660 C5-branched dibasic acid metabolism 6.59E−04 4
ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 1.80E−03 5 4.34E−02 4
ko00010 Glycolysis/gluconeogenesis 7.74E−03 5
ko00791 Atrazine degradation 2.89E−02 2
ko01502 Vancomycin resistance 1.10E−02 3
ko00983 Drug metabolism, other enzymes 3.28E−02 3
ko00720 Carbon fixation pathways in prokaryotes 1.24E−02 3