. 2020 Oct 28;86(22):e02138-20. doi: 10.1128/AEM.02138-20

TABLE 2.

Mutations identified in lab-adapted phage isolates

Nucleotide position^a	Gene homologs			Description^c	Mutation type^d	Nucleotide			Amino acid		Phage sample	Characteristic(s)^f
Nucleotide position^a	LP-125	LP-048	A511	Description^c	Mutation type^d	LP-125	LP-048	Alt^e	WT	Alt	Phage sample	Characteristic(s)^f
70807	LP125_108	LP048_098	gp99	Baseplate protein	MS	T	T	C	Ile	Thr	LP-Mix_6.1	Infects Rha⁻, Infects ST 3c
83734 (76232)^b	LP125_117	LP048_107	gp108	Short tail fiber (RBP)^c	MS	C	C	A	Asn	Lys	LP-048_m5	Decreased host range
83744	LP125_117	LP048_107	gp108	Short tail fiber (RBP)	MS	G	G	A	Glu	Lys	LP-125_m8	Infects Rha⁻, Infects ST 3c
83922	LP125_117	LP048_107	gp108	Short tail fiber (RBP)	MS	C	C	A	Thr	Lys	LP-Mix_6.2	Cannot infect Rha⁻
84334	LP125_118	LP048_108	gp109	Putative assembly chaperone protein	MS	T	T	C	Val	Ala	LP-Mix_6.2	Cannot infect Rha⁻
84428	LP125_118	LP048_108	gp109	Putative assembly chaperone protein	MS	C	T	A	Asp	Glu	LP-Mix_6.1	Infects Rha⁻, Infects ST 3c

Nucleotide position is relative to LP-125 (RefSeq accession number NC_021781).

Nucleotide position in LP-048 (RefSeq accession number NC_024359) is indicated in parentheses.

RBP, receptor binding protein.

MS, missense.

Alt, alternate allele.

ST, serotype.