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. Author manuscript; available in PMC: 2021 Nov 21.
Published in final edited form as: Neuroscience. 2020 Sep 6;449:116–122. doi: 10.1016/j.neuroscience.2020.09.004

Table 1.

Subject demographics and characteristics of the primate MPTP model of PD.

Subject Species (Macaca) Sex Age (years) Weight (kg) MPTP TCD (mg) MDS OFF MDS ON Recording regions Recording states
Sa Mulatta F 6 5.5 - - - Putamen Normal
Gl Mulatta F 8 5.1 13.7 21 - Putamen, GPi PD, OFF
Va Mulatta F 7 7.6 10.8 20 - Motor Cortex, Putamen, GPi PD, OFF
Na Mulatta F 12 8.1 20.1 19 - Motor Cortex PD, OFF
Br Fascicularis M 6 5.8 7.6 22 9.5* Putamen PD, Off/ON
Ch Fascicularis M 7 6 3 20 6.5* Putamen PD, Off/ON
*

: L-Dopa treatment was not administered daily but only acutely for recording sessions. The L-Dopa methyl ester/benserazide doses given s.c during the recordings were 95/24 mg for Br and 90/22.5 mg for Ch. TCD = total cumulative dose of MPTP. MDS = motor disability score in the “OFF” or “ON” state (scale range 0–39). F = female; M = male; GPi = globus pallidus internus.