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. Author manuscript; available in PMC: 2021 Nov 3.
Published in final edited form as: Structure. 2020 Aug 11;28(11):1206–1217.e4. doi: 10.1016/j.str.2020.07.011

Figure 4. M1-Ub6 is visible at hRpn11 in SA-like and SD-like proteasome states in the absence of E6AP.

Figure 4.

(A, B) Side-by-side comparison of the refined cryo-EM density maps with segmentation for the SA-like state of ATP-γ-S-bound human 26S proteasome mixed 10-fold molar excess non-cleavable M1-Ub6 without (A) or with (B) E6AP.

(C, D) Side-by-side comparison of the refined cryo-EM density maps with segmentation for the SD-like state of ATP-γ-S-bound human 26S proteasome mixed 10-fold molar excess non-cleavable M1-Ub6 without (A) or with (B) E6AP. The color scheme follows that of Figure 2B. The orientation displayed in (A)-(D) is identical for the CP.

See also Figure S4.