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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Cancer Res. 2020 Sep 15;80(21):4828–4839. doi: 10.1158/0008-5472.CAN-20-1030

Fig. 5: Milk-derived cells express luminal-differentiated cell enriched genes.

Fig. 5:

A) MDS plot of RNA-seq data of cells derived from breast milk of six donors. Note RNA expression differences between cells of the right and the left breast milk irrespective of whether one of the breasts had cancer (M1) or phenotypically aberrant cells (M2 and M10). B) qRT-PCR analyses of RNA from milk-derived cells for the expression of FOXA1 and GATA3. RNAs from milk-derived cells were analyzed in biologic triplicates. C) Left breast milk-derived cells of M10 express high levels of stemness-associated protein TP63 compared to the right breast milk-derived cells. TP63 expression was also higher in the right breast milk-derived cells of M1. Cell extracts obtained from three independent batch of cells were analyzed in case of M1.