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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Cancer Res. 2020 Sep 15;80(21):4828–4839. doi: 10.1158/0008-5472.CAN-20-1030

Fig. 6: Milk-derived cells of M1-right, M2-right and M10-left breasts contain driver mutations.

Fig. 6:

A) Summary of somatic mutation patterns revealed through whole genome sequencing of DNA from indicated samples. DNA from blood of individual donor was sequenced for comparison. Mutation frequency in DNA was similar in breast milk-derived cells with and without enrichment of cells with cancer stem cell phenotype. B) Schematic view of few of the driver mutations observed in cells from M1-right, M2-right and M10-left breast milk-derived cells. Various characterized domains of the corresponding proteins are indicated. C) Frequency of mutations in HDAC6, SMARCC2, NF1 and KMT2D in breast cancer. Data were generated using the cBioportal database.