Table 2.
Top six enriched KEGG pathways detected among 52 significantly upregulated genes (FDR <0.05) in BOECs in response to non-contact co-culture with spermatozoa following 10 h of incubation. Columns ‘Gene IDs’ and ‘Gene count’ show the significantly upregulated genes and the number of significantly upregulated genes that belong to the corresponding pathway
| Pathway ID | Pathway description | FDR | Gene IDs | Gene count |
|---|---|---|---|---|
| bta04913 | Ovarian steroidogenesis | 0.003 | CYP1A1, CYP1B1, PTGS2, PLA2G4A | 4 |
| bta00830 | Retinol metabolism | 0.012 | CYP1A1, DHRS3, UGT1A6 | 3 |
| bta05204 | Chemical carcinogenesis | 0.012 | CYP1A1, CYP1B1, PTGS2, UGT1A6 | 4 |
| bta00140 | Steroid hormone biosynthesis | 0.013 | CYP1A1, CYP1B1, UGT1A6 | 3 |
| bta00980 | Metabolism of xenobiotics by cytochrome P450 | 0.039 | CYP1A1, CYP1B1, UGT1A6 | 3 |
| bta04060 | Cytokine-cytokine receptor interaction | 0.039 | TNFRSF11B, GDF15, TNFSF15, CXCR4 | 4 |