Table 4.

Two multivariable models for 28-day and ICU mortality of the sepsis cohort.

	Odds ratio	95% confidence	p
		interval
Multivariable model 1: 28-day mortality
Arylesterase activity (AEA)	0.76	0.59–0.98	0.032
(per 10 mM/min/ml serum increase)
SOFA score (per 1 point increase)	1.11	0.91–1.35	0.292
Age (per 5 years increase)	1.27	0.99–1.64	0.064
C-reactive protein	1.71	0.99–2.94	0.053
(per 100 mg/l increase)
Multivariable model 2: ICU mortality
Arylesterase activity (AEA) (per 10 mM/min/ml serum increase)	0.74	0.57–0.96	0.026
SOFA score (per 1 point increase)	1.30	1.06–1.59	0.010

For multivariable analysis, we always considered the SOFA score and, additionally, all variables with a univariable p of association with the outcome of ≤ 0.05. Albumin was omitted from multivariable model 1 due to strong collinearity with C-reactive protein.

AEA, arylesterase activity; SOFA, sequential organ failure assessment.