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. 2020 Nov 25;50(6):391–400. doi: 10.4041/kjod.2020.50.6.391

Figure 4.

Figure 4

Relative mRNA expression of genes encoding COL1A1, LOX, ELN, MMP 1, MMP 12, and TIMP 1 in gingival tissue of beagle dogs after sulforaphane treatment. COL1A1 (A), LOX (B), ELN (C), MMP 1 (D), MMP 12 (E), and TIMP 1 (F) mRNA levels in gingival tissue were quantified by real-time polymerase chain reaction. The symbol (*) indicates statistical significance between the control group and experimental group (*p < 0.05, Wilcoxon signed rank test).

DMSO, Dimethylsulfoxide; COL1A1, collagen type I alpha 1; LOX, lysyl oxidase; ELN, elastin; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinase.