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. 2020 Nov 3;10:18936. doi: 10.1038/s41598-020-75850-8

Figure 4.

Figure 4

Processing of necrotic bodies in endosomes by macrophages and glia. (A–L) Expression of early (Rab5) and late (Rab7) endosomal markers in the different cell types after challenge with necrotic cells. (A–F) Example images of Western Blots for Rab5 and Rab7; (A–C) show 0–180 min, (D–F) show 0–48 h. (G–L) Quantification of Rab5 and Rab7 protein expression. Bar graphs represents relative protein expression of Rab5 and Rab7 to a housekeeping protein (β-actin), with data from three independent experiments ± SEM. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.0001 (one-way ANOVA with Dunnett’s multiple comparison post-hoc test).