Table 1.

Sequences of the Considered Peptides (SIM2 and SIM3) and the SIM2-SIM3 Peptide Considered by Xu et al

Peptide	Sequence
SIM2	(rETAG)DEIVDLTCE(SLEPrw)
SIM3	(TCESL)EPVVVDLTHND(Sw)
SIM2-SIM3	TVGDEIVDLTCESLEPVVVDLTHND

The SIMs themselves are underlined. The residues in parenthesis are cut off in our model but present in experiments by Kung et al. Small letters indicate residues that are not part of RNF4 but have been added by Kung et al. Note that in our smaller peptides, the termini were amidated/acetylated.