Figure 2.

The heat map shows the log of the calculated looping probability for pairs of nucleosomes along the chromosome, with an NFR of 1000 bp. The white section from −1000 to 0 bp corresponds to the effective NFR. The dots appearing in that section correspond to looping with the nucleation site, which was inserted at −277 bp in the methylation-spreading experiments and, thus, lies within the effective NFR (16). The minus sign, star, and plus sign correspond to the −1 nucleosome, nucleation site, and +1 nucleosome, respectively. To see this figure in color, go online.