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. 2020 Nov 4;10:18994. doi: 10.1038/s41598-020-76130-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cytokine protein levels and correlation with Treg cell frequencies in the validation cohort (n = 49). Treg cell frequencies in association with (A) TGF-β, (B) IL-10, or (C) IL-6 at a low or high level. (D) GM-CSF, GRO-alpha, IFN-alpha, IL-12p70, IL-1beta, IL-15, IL-17A, IL-2, TNF-alpha, I-23, IL-27, IL-5, and IL-7 cytokines in plasma associated with durable clinical benefiters (DCB) or non-durable clinical benefiters (NDB). The center value is mean ± SEM, and the error bar represents the standard deviation of the mean.