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. 2020 Nov 4;3:644. doi: 10.1038/s42003-020-01359-5

Fig. 2. Recombinant MUC1-ST can induce the differentiation of monocytes into TAMs in an M-CSF independent manner.

Fig. 2

a Bright field images of representative healthy donor monocytes treated with indicated factors for 7 days in serum-free media. b Number of viable cells from monocytes treated with indicated factors for 7 days in serum-free media (n = 7 biologically independent samples). c Phenotype of monocytes treated with indicated factors for 7 days in serum-free media (n = 8 biologically independent samples). d, e % viable cells (d), and number of viable cells (e) from monocytes cultured with either MCSF or MUC1-ST for 7 days in serum-free media in the presence of anti-MCSF neutralising antibodies or isotype control (n = 4 biologically independent samples). f Summary of phenotype for cells in (d). Standard error of mean shown and paired t test used for statistical analysis. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.