Table 2.
Demographic characteristics of the peripheral tissues samples.
| Peripheral tissue | Subjects (n) | Age (mean ± SD) | Gender (M/F) | ||||
|---|---|---|---|---|---|---|---|
| Control | Schizophrenia | p-valuea | Control | Schizophrenia | p-valuea | ||
| Primary datasets | |||||||
| Blood (PBMCs) | 29 HC/43 SZ | 23.02 ± 4.03 | 23.90 ± 4.08 | 0.378 | 29/0 | 43/0 | 1 |
| Olfactory epithelium | 19 HC/19 SZ | 39.7 ± 11.6 | 38.9 ± 11.4 | 0.829 | 13/6 | 13/6 | 1 |
| Skin fibroblasts | 20 HC/20 SZ | 48.4 ± 12.2 | 44.6 ± 12.7 | 0.340 | 9/11 | 10/10 | 0.758 |
| Validation dataset | |||||||
| Blood (whole blood) | 96 HC/106 SZ | 39.3 ± 14.2 | 39.6 ± 10.7 | 0.877 | 42/54 | 76/30 | 1 × 10−4 |
PBMCs peripheral blood mononuclear cells, HC healthy controls, SZ individuals with schizophrenia
aUnpaired t-tests and Fisher exact tests were conducted to assess group differences for continuous and discrete variables, respectively.