Table 4.
Comparison of receiver operating characteristics curves of the different models predicting any-stage and stage III/IV endometriosis.
| Training sample | Validation sample | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AUC | 95% CI | Z Score* | P-value* | IDI, % | 95% CI | P-value | AUC | 95% CI | Z Score* | P-value* | IDI, % | 95% CI | P-value | |
| Any-stage endometriosis | ||||||||||||||
| Full model | 0.792 | 0.759–0.825 | – | – | – | – | – | 0.760 | 0.710–0.810 | |||||
| Full model no patients' history and symptom | 0.730 | 0.696–0.764 | −4.58 | <0.001 | −7.18 | −9.18/−5.19 | <0.001 | 0.735 | 0.686–0.783 | −1.46 | 0.14 | −4.7 | −7.47/−1.94 | <0.001 |
| Full model no palpable nodularity | 0.783 | 0.749–0.816 | −1.94 | 0.052 | −1.25 | −2.04/−0.45 | 0.002 | 0.763 | 0.712–0.813 | 0.34 | 0.73 | −0.75 | −2.1/−0.61 | 0.28 |
| Full model no endometrioma diagnosed by TVS | 0.759 | 0.723–0.795 | −4.33 | <0.001 | −5.31 | −6.88/−3.74 | <0.001 | 0.734 | 0.681–0.787 | −3.14 | 0.002 | −4.37 | −6.24/−2.5 | <0.001 |
| Full model no tubal pathology | 0.753 | 0.718–0.789 | −3.18 | 0.001 | −6.20 | −8.13/−4.27 | <0.001 | 0.690 | 0.635–0.746 | −3.67 | <0.001 | −8.87 | −11.91/−5.83 | <0.001 |
| Endometrioma diagnosed on TVS only | 0.601 | 0.580–0.623 | −11.57 | <0.001 | −16.4 | −19.28/−13.53 | <0.001 | 0.596 | 0.567–0.625 | −6.69 | <0.001 | −15.58 | −19.92/−11.23 | <0.001 |
| Stage III–IV endometriosis | ||||||||||||||
| Full model | 0.885 | 0.848–0.922 | – | – | – | – | – | 0.799 | 0.723–0.875 | – | – | – | – | – |
| Full model no patient history and symptom | 0.824 | 0.777–0.871 | −4.08 | <0.001 | −1.73 | −2.81/−0.64 | 0.002 | 0.780 | 0.702–0.857 | −0.81 | 0.42 | −2.49 | −4.01/−0.97 | 0.001 |
| Full model no palpable nodularity | 0.870 | 0.830–0.909 | −1.76 | 0.08 | −1.03 | −1.80/−0.25 | 0.009 | 0.798 | 0.724–0.872 | −0.12 | 0.90 | −1.20 | −2.47/−0.07 | 0.064 |
| Full model no endometrioma diagnosed by TVS | 0.779 | 0.734–0.824 | −6.11 | <0.001 | −9.50 | −12.45/−6.54 | <0.001 | 0.705 | 0.631–0.780 | −3.77 | <0.001 | −7.66 | −11.71/−3.61 | <0.001 |
| Full model no tubal pathology | 0.886 | 0.850–0.921 | 0.15 | 0.88 | −0.48 | −0.86/−0.10 | 0.014 | 0.799 | 0.723–0.875 | −0.065 | 0.95 | −0.41 | −0.93/−0.10 | 0.12 |
| Endometrioma diagnosed on TVS only | 0.769 | 0.726–0.812 | −6.19 | <0.001 | −3.99 | −5.35/−2.63 | <0.001 | 0.764 | 0.702–0.826 | −1.22 | 0.22 | −4.39 | −6.41/−2.36 | <0.001 |
*
For AUC comparison. AUC, area under the ROC curve; CI, confidence interval; IDI, integrated discrimination improvement.