Table 2.

Associations between adherence status and the risk of death among patients with colon cancer stratified by age: results from the National Cancer Database^a

Strata	Adherent		Non-adherent		HR (95% CI)b	HR (95% CI)c
	No. of patients	No. of deaths	No. of patients	No. of deaths
Aged <50	36,410	12,593	8,689	3,389	1.71 (1.65-1.78)	1.71 (1.64-1.78)
Aged 50-64	101,775	32,853	28,781	13,817	2.02 (1.98-2.07)	2.01 (1.97-2.05)
Aged 65-74	89,593	30,860	32,924	18,812	2.28 (2.24-2.33)	2.24 (2.20-2.29)
Aged ≥75	102,891	47,789	85,221	61,614	2.27 (2.23-2.30)	2.23 (2.20-2.26)

Abbreviations: HR, Hazard Ratio.

^aAdherence to NCCN treatment guidelines as the reference.

^bAdjustment for age, sex, race, residence, education, income, facility type, insurance, histology, grade, TNM stage.

^cAdditional adjustment for Charlson comorbidity score.