Figure 5.

ARHGEF7 and KLHL2 protein are negatively correlated in renal cancer specimens. A. Representative images of IHC analysis of ARHGEF7 and KLHL2 protein expression on tissue microarray (n = 72 paired renal cancer tissue specimens). B. Box plots of ARHGEF7 and KLHL2 protein expression based on their staining index in paired tumor tissue and normal renal tissues. C, D. Box plots of ARHGEF7 and KLHL2 protein expression based on their IS in renal cancer specimens at different clinical stages. E. KLHL2 and ARHGEF7 staining patterns in 72 paired ccRCC cases. F. Correlation analysis of the IS of expression levels of ARHGEF7 and KLHL2 proteins in human renal cancer specimens.