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. 2020 Oct 1;10(10):3328–3344.

Figure 5.

Figure 5

CEBPG directly binds to the regulatory elements of genes involved in the PI3K-AKT signaling pathway. A. Based on the ChIP-Seq and RNA-Seq data, Venn diagrams showing the numbers of overlapped genes associated with the PI3K-AKT signaling pathway. The CEBPG ChIP-Seq data of HepG2 cell line was downloaded from GSE96281. TSS-proximal, <1 kb of TSS; TSS-distal, >1 kb of TSS; TSS, Transcription Start Site. B. Various ChIP-Seq profiles of CCND1 and MYC gene loci. The H3K27ac ChIP-Seq data of various ESCC cell lines were downloaded from GSE106563. The CEBPG ChIP-Seq data of HepG2 cells line was downloaded from GSE96281. C. The ChIP-qPCR for CEBPG at the CCND1 and MYC loci in KYSE150 and KYSE140 cell lines. NC was used as a negative control. Unpaired t test. *, P<0.05; **, P<0.01; ns, not significant.