FIG 4.

HIV-1 Gag cleavage efficiency in resistant (Res) versus susceptible (Susc) isolates. (A) Representative Western blot of virus-containing supernatant at increasing drug doses, using a p24 antibody. Mass (in kilodaltons) is indicated on the left. MA, matrix (p17); CA, capsid (p24); NC, nucleocapsid; SP1, spacer peptide 1. (B) Ratios of p24/p41 at increasing drug doses. Data are means and standard deviations from 2 independent experiments. In each pair, the left bar represents the wild type and the right bar represents resistant virus.