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Phylogenetic relationships between viral Gag-protease plasma-derived sequences isolated at baseline (pre-PI) and at two failure time points (VF1 and VF2). The maximum-likelihood tree has bootstrap support indicated at the nodes. The outlier is HXB2, a subtype B virus. VF1, viral failure 1 at 41 months after initiation of protease inhibitor therapy; VF1, viral failure 2 at 64 months after initiation of protease inhibitor therapy.
