Table 1.
Up-regulated hub genes in mutated group
| Name | Degree | Closeness Centrality | Betweenness Centrality | Gene description |
|---|---|---|---|---|
| APOB | 22 | 0.302222 | 0.248282 | Apolipoprotein B-100 |
| ITIH2 | 15 | 0.261538 | 0.021842 | Inter-alpha-trypsin inhibitor heavy chain H2 |
| SERPINA10 | 15 | 0.262042 | 0.033403 | Protein Z-dependent protease inhibitor |
| CPB2 | 14 | 0.257089 | 0.016069 | Carboxypeptidase B2 |
| TTR | 14 | 0.279835 | 0.147093 | Transthyretin |
| PROC | 13 | 0.253731 | 0.024379 | Vitamin K-dependent protein C |
| TMPRSS6 | 13 | 0.259542 | 0.05632 | Transmembrane protease serine 6 |
| FTCD | 13 | 0.265107 | 0.053097 | Formimidoyltransferase-cyclodeaminase |
| UGT1A6 | 12 | 0.261036 | 0.087723 | UDP-glucuronosyltransferase 1-6 |
| ORM1 | 11 | 0.270916 | 0.027003 | Alpha-1-acid glycoprotein 1 |