Table 2.
Down-regulated hub genes in mutated group
| Name | Degree | Closeness Centrality | Betweenness Centrality | Gene description |
|---|---|---|---|---|
| PTPRC | 24 | 0.45188285 | 0.21907957 | Receptor-type tyrosine-protein phosphatase C |
| FGF2 | 20 | 0.44081633 | 0.18552069 | Fibroblast growth factor 2 |
| CTLA4 | 18 | 0.38571429 | 0.06445833 | Cytotoxic T-lymphocyte protein 4 |
| VCAM1 | 15 | 0.40909091 | 0.09752962 | Vascular cell adhesion protein 1 |
| PTGS2 | 14 | 0.42023346 | 0.16118209 | Prostaglandin G/H synthase 2 |
| BDNF | 14 | 0.4 | 0.12983006 | Brain-derived neurotrophic factor |
| NCAM1 | 12 | 0.38709677 | 0.04818733 | Neural cell adhesion molecule 1 |
| TNFSF11 | 11 | 0.41860465 | 0.05839004 | Tumor necrosis factor ligand superfamily member 11 |
| CD3G | 11 | 0.35409836 | 0.05727753 | T-cell surface glycoprotein CD3 gamma chain |
| IL21R | 11 | 0.36 | 0.02923529 | Interleukin-21 receptor |