Table 4.
Effect size of nonHDLc/HDLc on NAFLD in prespecified and exploratory subgroups
| Characteristic | No. of participants | Effect Size (95% CI) | P for interaction |
|---|---|---|---|
| Sex | 0.974 | ||
| Male | 7690 | 2.1 (1.9, 2.2) | |
| Female | 8483 | 2.1 (1.9, 2.2) | |
| Age (year) | 0.004 | ||
| 14-33 | 5079 | 2.2 (2.0, 2.5) | |
| 34-46 | 5391 | 2.2 (2.0, 2.4) | |
| 47-95 | 5703 | 1.9 (1.7, 2.0) | |
| ALT | 0.532 | ||
| 1-13 | 3977 | 1.9 (1.7, 2.2) | |
| 14-19 | 3786 | 2.0 (1.8, 2.2) | |
| 20-674 | 4365 | 1.9 (1.8, 2.0) | |
| AST | 0.004 | ||
| 5-18 | 3197 | 2.5 (2.2, 2.8) | |
| 19-23 | 4816 | 2.1 (2.0, 2.3) | |
| 24-311 | 4115 | 1.9 (1.7, 2.0) | |
| Albumin | 0.736 | ||
| 11-42 | 3289 | 2.0 (1.8, 2.2) | |
| 43-45 | 6264 | 2.0 (1.9, 2.2) | |
| 46-55 | 5241 | 2.0 (1.8, 2.1) | |
| BUN | <0.001 | ||
| 1-3 | 3133 | 2.6 (2.3, 2.9) | |
| 4-4 | 5342 | 2.3 (2.2, 2.6) | |
| 5-31 | 7697 | 1.8 (1.7, 1.9) | |
| Cr | <0.001 | ||
| 10-67 | 5282 | 1.7 (1.5, 1.9) | |
| 68-84 | 5300 | 2.1 (1.9, 2.3) | |
| 85-1004 | 5590 | 2.2 (2.0, 2.3) | |
| UA | 0.018 | ||
| 17-232 | 5336 | 2.2 (1.9, 2.5) | |
| 233-310 | 5406 | 1.8 (1.6, 1.9) | |
| 311-706 | 5430 | 1.8 (1.7, 1.9) | |
| FPG | 0.067 | ||
| 2.54-4.83 | 5278 | 2.1 (1.9, 2.4) | |
| 4.84-5.2 | 5401 | 2.1 (2.0, 2.3) | |
| 5.21-20.87 | 5493 | 1.9 (1.7, 2.0) | |
| TC | 0.044 | ||
| 2-4.29 | 5384 | 2.3 (2.1, 2.6) | |
| 4.3-4.93 | 5361 | 2.0 (1.8, 2.2) | |
| 4.94-15.92 | 5428 | 2.0 (1.8, 2.1) | |
| TG | 0.636 | ||
| 0.23-0.88 | 5295 | 1.5 (1.3, 1.9) | |
| 0.89-1.32 | 5402 | 1.4 (1.2, 1.6) | |
| 1.33-30.39 | 5476 | 1.5 (1.4, 1.6) | |
| BMI | 0.538 | ||
| 14.53-20.42 | 5353 | 1.9 (1.5, 2.3) | |
| 20.43-22.46 | 5424 | 1.8 (1.6, 2.0) | |
| 22.47-25 | 5396 | 1.7 (1.6, 1.8) | |
| SBP | <0.001 | ||
| 77-111 | 5064 | 2.7 (2.4, 3.0) | |
| 112-125 | 5575 | 2.0 (1.9, 2.2) | |
| 126-208 | 5514 | 1.7 (1.6, 1.8) | |
| DBP | 0.002 | ||
| 45-66 | 4872 | 2.2 (2.0, 2.5) | |
| 67-76 | 5824 | 2.1 (1.9, 2.3) | |
| 77-125 | 5457 | 1.8 (1.7, 1.9) |