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. 2020 Oct 1;13(10):2524–2533.

Figure 2.

Figure 2

MiR-451a suppresses stomach cancer cell proliferation. After miR-451a was transfected alone or with the CAV1 expression plasmid into the HGC-27 or MKN-45 cells, the cellular proliferation was analyzed using MTT (A) and EdU assays (B, C), and the cell cycle phase was determined by PI staining (D, E). *P < 0.05, miR-451a vs miRNA NC; **P < 0.01, miR-451a vs miRNA NC; ##P < 0.01, miR-451a + CAV1 vs miR-451a; ***P < 0.001, miR-451a vs miRNA NC; ###P < 0.001, miR-451a + CAV1 vs miR-451a; ####P < 0.0001, miR-451a + CAV1 vs miR-451a. miR-451a+CAV1: miR-451a was co-transfected with the CAV1 expression plasmid; CAV1: caveolin-1; miRNA NC: the negative control of miR-451a.