Figure 3.
MiR-451a promotes apoptosis in stomach cancer cells. After the HGC-27 and MKN-45 cells were transfected with miR-451a alone or with miR-451a and the CAV1 expression plasmid, the apoptosis was detected using the Annexin V-FITC/PI apoptosis detection kit. A. Representative images of the apoptosis analysis. B. Histogram representing the percentage of apoptotic cells under various conditions. **P < 0.01, miR-451a vs miRNA NC; ##P < 0.01, miR-451a + CAV1 vs miR-451a. miR-451a+CAV1: miR-451a was co-transfected with the CAV1 expression plasmid; CAV1: caveolin-1; miRNA NC: the negative control of miR-451a.