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. 2020 Oct 1;13(10):2524–2533.

Figure 4.

Figure 4

Mir-451a interferes with the migration and invasion of stomach cancer cells. MiR-451a was transfected alone or with the CAV1 expression plasmid into HGC-27 or MKN-45 cells. A. The effect of miR-451a on cellular migration was examined using a transwell assay. B. Histogram representing the number of migrated cells per field of view under various treatment conditions. C. Representative images of the invasion analysis. D. Histogram representing the number of invasive cells per field of view under various conditions. **P < 0.01, miR-451a vs miRNA NC; ***P < 0.001, miR-451a vs miRNA NC; ###P < 0.001, miR-451a + CAV1 vs miR-451a; ####P < 0.0001, miR-451a + CAV1 vs miR-451a. miR-451a+CAV1: miR-451a was co-transfected with the CAV1 expression plasmid; CAV1: caveolin-1; miRNA NC: the negative control of miR-451a.