. 2020 Nov 5;226(1):152021. doi: 10.1016/j.imbio.2020.152021

Table 3.

RGD binding Integrins, their receptors and their role in virus attachment and cell signaling as sourced from UniProt KB database.

S.N.	Integrin	UniProt ID	Receptor	Virus Attachment	Function
1	αvβ3 ITGAV-ITGB3 CD61	P06756 P05106	CD40LG FGF1/FGF2 CX3CL1 PLA2G2A NRG1 IGF2 IL-1B FBN1 CD40-LG IGF2 Ca⁺² Binding Sites 260–268; 314–322; 379–387; 443–451	Herpes virus 8 HHV-8 Coxsackievirus A9 Hantaan virus Cytomegalovirus/HHV-5 Human metapneumovirus Human parechovirus 1 West nile virus HIV-1	FGF1 signaling FGF2 signaling NRG1-ERBB signaling CX3CL1 signaling 1L-1B signaling CD40-CD40L signaling IGF2 signaling
2	αvβ5 ITGAV-ITGB5	P06756 P18084	Fironectin	Adenovirus type c Coxsackievirus A9 CoxsackievirusB1	TGF-β1 singaling
3	αvβ6 ITGAV-ITGB6	P06756 P18564	Fibronectin Cytotactin TGF-β1 FBN1	Coxsackievirus A9 Coxsackievirus B1 Herpes simplex virus-1 HHV-1	TGF-β1 activation Clathrin-mediated endocytosis
4	αvβ8 ITGAV-ITGB8	P06756 P26012	Fibronectin TGF-β1	Data not found	TGF-β1 activation
5	α5β1 ITGA5-ITGB1 CD29	P08648 P05556	Fibrinogen Fibronectin PLA2G2A CD40LG IL1B FBN1 Ca⁺² Binding Sites 280–288; 334–342; 401–409; 465–473	Cytomegalovirus/HHV-5 Epstein-Barr virus/HHV-4 Human parvovirus B19 Mammalian reovirus HIV-1 Human metapneumovirus	CD40-CD40L signaling IL1B signaling
6	α8β1 ITGA8-ITGB1	P53708 P05556	TNC FN1 SPP1 TGFB1/TGFB3 VTN NPNT Ca⁺² Binding Sites 329–337; 395–404; 459–467	Data not found	TGF-β1 signaling