Table 1. A summary of de novo phasing SFX studies and selected de novo phasing serial crystallography studies at synchrotron sources.

Sample	Element	Bijvoet ratio (%)	Phasing method	Minimal number of images	Resolution (Å)	Photon energy (keV)	Facility	Publication
A2A	S	2.5	SAD	50000	2.65	4.57	SwissFEL	This work
A2A	S	1.5	SAD	500000	2.5	6.0	LCLS	Batyuk et al. (2016 ▸)
A2A	S	1.5	SAD	243537	2.67	6.0	SLS	Weinert et al. (2017 ▸)
Thaumatin	S	3.2	SAD	20000	2.65	4.57	SwissFEL	This work
Thaumatin	S	2.0	SAD	50000	1.95	6.06	SwissFEL	This work
Thaumatin	S	2.0	SAD	150000	2.1	6.0	LCLS	Nass et al. (2016 ▸)
Lysozyme	S + Cl	1.9	SAD	150000	2.1	7.0	SACLA	Nakane et al. (2015 ▸)
Se-B SA	Se	1.2	SAD	481079	1.9	12.8	LCLS	Hunter et al. (2016 ▸)
Stem	Se	3.7	SAD	13000	1.4	13.0	SACLA	Yamashita et al. (2017 ▸)
ACG	Se	2.2	SAD	60000	1.5	13.0	SACLA	Yamashita et al. (2017 ▸)
CuNiR	Cu	1.6	SAD	155588	1.6	10.8	SACLA	Fukuda et al. (2016 ▸)
LRE	Hg	4.2	SAD	11000	1.5	12.6	SACLA	Yamashita et al. (2017 ▸)
LRE	Hg	4.2	SIRAS	18000	1.7	12.6	SACLA	Yamashita et al. (2015 ▸)
BinAB	Hg, Gd, I	–	MIRAS	357765	2.4, 2.35, 2.6	8.8	LCLS	Colletier et al. (2016 ▸)
bR	I	10.5	SAD	23347	2.1	7.0	SALCA	Nakane et al. (2016 ▸)
Lysozyme	Gd	10.2	SAD	5000	1.9	9.0	SACLA	Gorel et al. (2017 ▸)
Lysozyme	Gd	10.2	MAD	5000	1.9, 2.0	9.0 + 7.0	SACLA	Gorel et al. (2017 ▸)
Lysozyme	Gd	11.0	SAD	60000	2.1	8.5	LCLS	Barends et al. (2014 ▸)
Proteinase K	Pr	4.8	SAD	3000	1.5	10	SACLA	Sugahara et al. (2017 ▸)
Proteinase K	Pr	4.8	SIRAS	2000	1.5	10	SACLA	Sugahara et al. (2017 ▸)