Table 5.

Significant changes in protein levels associated with the pentose phosphate pathway in MCF7 cells overexpressing mitochondrial fission factor (MFF).

Symbol	Gene name	Fold change
Pentose phosphate pathway
G6PD	Glucose-6-phosphate dehydrogenase	−136.908
PGD	Phosphogluconate dehydrogenase	4.903
PGLS	6-phosphogluconolactonase	1.776
RPE	Ribulose-5-phosphate-3-epimerase	2.25
RPIA	Ribose 5-phosphate isomerase A	−11.28
TALDO1	Transaldolase 1	−6.741
TKT	Transketolase	−82.993

Fold change of proteins detected in MCF7-MFF vs. MCF7-Control cells. Red: Up-regulated proteins; Green: Down-regulated proteins. Proteomics was performed as described in Materials and Methods. Statistical analyses were performed using ANOVA and 1.5-fold-changes in proteins with a p < 0.05 were considered. Dataset containing proteins with significant altered expression profile were imported into the Ingenuity Pathway Analyses (IPA) software, which groups the differentially expressed proteins into known functions and pathways.