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. 2020 Aug 12;35(5):338–347. doi: 10.1152/physiol.00013.2020

FIGURE 1.

FIGURE 1.

The period spent free of chronic disease is defined as the healthspan

Once there is a chronic disease, which is often followed by other chronic diseases, the healthspan has ended. Most treatments focus on the period spent with disease, which is in individuals who can have vastly different physiology from those in the healthspan. Therefore, it is crucial to understand the effects of proposed treatments for prolonging the healthspan in healthy individuals and in individuals who may be practicing other health-promoting behaviors.