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Weight loss, kidney function, and injury in C57BL/6 mice treated with repeated administration of 9 mg/kg cisplatin. A: percent body weight loss. B: blood urea nitrogen (BUN) levels measured in plasma. C: neutrophil gelatinase-associated lipocalin (NGAL) levels measured in urine. Statistical analysis was determined by two-way ANOVA followed by Tukey’s post-hoc test. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.
